Pharmacology of Drug Stereoisomers
English | 2022 | ISBN: 9811923191 | 218 Pages | PDF EPUB (True) | 16 MB
The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors put special emphasis on general problems of the influence of stereoisomerism on pharmacological and adverse effects of drugs. A classification of drugs based on stereochemical properties of their isomers is proposed. Possibilities of interaction of stereoisomers in racemic mixtures are discussed. A considerable portion of the book is devoted to pharmacological action of the main groups of drugs whose structure includes asymmetric atoms (that is, drugs with several isomers). Detailed attention is paid to advisability of developing single isomer drugs and to the specifics of their study at the stage of preclinical and clinical trials.

Jane Austen, "Persuasion"
English | ISBN: 1440468397 | 2008 | 150 pages | EPUB, MOBI | 880 KB + 582 KB
This is a beautiful, large format ("6x9") edition of Jane Austen's classic romance, Persuasion.

Michael Paulsen, "Pedagogy in the Anthropocene: Re-Wilding Education for a New Earth "
English | ISBN: 3030909794 | 2022 | 402 pages | PDF | 5 MB
This book explores new pedagogical challenges and potentials of the Anthropocene era. The authors argue that this new epoch, with an unstable climate, new kinds of globally spreading viruses, and new knowledges, calls for a new way of educating and an alertness to new philosophies of education and pedagogical imaginations, thoughts, and practices. Addressing the linkages between the Anthropocene and Pedagogy across a broad pedagogical spectrum that is both formal and informal, the editors and their contributors emphasize a re-imagining of education that serves to deepen our understanding of the capacities and values of life.

Daniel Larsen, Sven O. Egenhoff, Neil S. Fishman, "Paying Attention to Mudrocks: Priceless!"
English | 2015 | ISBN: 0813725151 | PDF | pages: 173 | 12.3 mb
Siliciclastic mudrocks, often termed shales, represent more than two thirds of all sedimentary rocks on Earth, yet they are probably the least understood. This volume brings together eight articles on current research on mudrocks of academic and industry importance that help clarify key aspects of sedimentology, mineralogy, origin, and resource distribution in mudrocks.

Pascal's Triangle: A Study in Combinations by Jason VanBilliard
English | June 17, 2014 | ASIN: B00L3O2KPA, ISBN: 1499730616 | True AZW3 | 106 pages | 0.5 MB
You will enjoy this book if you are mathematically curious and have a reasonably sound high school mathematics background.

Pascal's Arithmetical Triangle: The Story of a Mathematical Idea (Dover Books on Mathematics) by A. W. F. Edwards
English | June 12, 2019 | ISBN: 0486832791 | True EPUB | 224 pages | 15.2 MB
"An impressive culmination of meticulous research into original sources, this definitive study constitutes the first full-length history of the Arithmetic Triangle." - Mathematics of Computation

Parkrun: An Organised Running Revolution By David Hindley
2022 | 142 Pages | ISBN: 0367640635 | PDF | 2 MB
This is the first book to take an in-depth look at parkrun - the free, weekly, timed 5km run on a Saturday morning - and to examine why its participants love it so much and why it has been such an astonishing success.

Uwe Feist, Bruce Culver - Panzerkampfwagen Panther: 50th Anniversary Collectors Edition
Ryton Publications | 1995 | ISBN: N/A | English | 271 pages | PDF | 139.61 MB
This volume covers the history in photos and text of World War II's outstanding AFV, the legendary Panzerkampfwagen Panther. Extensively illustrated with over 500 photographs and 35th scale drawings by John L. Rue.

Harriet de Winton, "Painting Watercolor Botanicals: 34 Projects for Flowers, Foliage and More"
English | 2020 | ISBN: 1440300917 | EPUB | pages: 128 | 108.4 mb
Learn to create your own beautiful watercolor botanical art with more than 30 projects, as well as information on materials and basic techniques. The graceful, contemporary style of these flowers and foliage is attractive and accessible to all no matter your skill level.

Ownership: Reinventing Companies, Capitalism, and Who Owns What by Corey Rosen, John Case
English | September 13th, 2022 | ISBN: 1523000821 | 256 pages | True EPUB | 1.00 MB
Employee ownership creates stronger companies, helps workers build wealth, and fosters a fairer, more stable society. In this book, two leading experts show how it works-and how it can be greatly expanded.