Computational Geometry: Algorithms and Applications by Mark Berg, Otfried Cheong, Marc Kreveld, Mark Overmars
English | PDF | 2008 | 387 Pages | ISBN : 3540779736 | 2.8 MB
Computational geometry emerged from the ?eld of algorithms design and analysis in the late 1970s. It has grown into a recognized discipline with its own journals, conferences, and a large community of active researchers. The success of the ?eld as a research discipline can on the one hand be explained from the beauty of the problems studied and the solutions obtained, and, on the other hand, by the many application domains-computer graphics, geographic information systems (GIS), robotics, and others-in which geometric algorithms play a fundamental role. For many geometric problems the early algorithmic solutions were either slow or dif?cult to understand and implement. In recent years a number of new algorithmic techniques have been developed that improved and simpli?ed many of the previous approaches. In this textbook we have tried to make these modern algorithmic solutions accessible to a large audience. The book has been written as a textbook for a course in computational geometry, but it can also be used for self-study.

Comprehensive Preventive Dentistry By
2012 | 400 Pages | ISBN: 0813821681 | PDF | 23 MB
Comprehensive Preventive Dentistry provides one user-friendly resource that brings together information on the scientific basis and clinical practice of all aspects of preventive dentistry. This thorough and all-encompassing resource offers techniques and strategies for maintaining excellent oral health in patients through a regimen of preventive measures.Comprehensive Preventive Dentistry is grounded in a patient-centered, pre-emptive, and minimally invasive philosophy. The book begins by covering individual diseases, such as caries, periodontitis, and oral cancer, as well as therapies (sealants, fluoride) and other relevant conditions (toothwear, hypersensitivity). Additionally, concepts such as the role of diet and nutrition in oral health are discussed. Also covered are oral care products and new techological developments in caries diagnosis and risk assessment, periodontal disease and oral cancer, as well as new developments in home care products. A valuable and comprehensive companion that will appeal to dentists and dental hygienists, this helpful new book provides its readers with one authoritative resource that offers a reliable and helpful companion to practicing preventive dentistry.Content: Chapter 1 A Brief Introduction to Oral Diseases: Caries, Periodontal Disease, and Oral Cancer (pages 1-24): Hardy Limeback, Jim Yuan Lai, Grace Bradley and Colin RobinsonChapter 2 Caries Detection and Diagnosis (pages 25-42): Iain A. PrettyChapter 3 Diagnosis of Periodontal Diseases (pages 43-60): Jim Yuan LaiChapter 4 Oral Cancer (pages 61-80): Grace Bradley and Iona LeongChapter 5 Evidence?Based Dentistry (pages 81-98): Amir Azarpazhooh, David Locker and Prakeshkumar S. ShahChapter 6 The Role of Diet in the Prevention of Dental Diseases (pages 99-114): Paula MoynihanChapter 7 Probiotics and Dental Caries Risk (pages 115-118): Eva SoderlingChapter 8 Mechanical Plaque Removal (pages 119-145): Shirley GutkowskiChapter 9 The Role of Sugar Alcohols, Xylitol, and Chewing Gum in Preventing Dental Diseases (pages 146-158): Peter Milgrom and Kiet A. LyChapter 10 Preventing Dental Disease with Chlorhexidine (pages 159-179): Hardy Limeback and Ross PerryChapter 11 Ozone in the Prevention of Dental Diseases (pages 180-194): Hardy Limeback and Amir AzarpazhoohChapter 12 Protection of the Dentition (pages 195-210): Hardy LimebackChapter 13 Tooth Erosion (pages 211-217): W. Peter HolbrookChapter 14 The Etiology, Diagnosis, and Management of Dentin Hypersensitivity (pages 218-232): Hardy LimebackChapter 15 Caries Risk Assessment (pages 233-250): Ferne Kraglund and Hardy LimebackChapter 16 Fluoride Therapy (pages 251-282): Hardy Limeback and Colin RobinsonChapter 17 Dental Sealants (pages 283-297): Hien Ngo and W. Kim SeowChapter 18 Strategies for Remineralization (pages 298-312): Laurence J. WalshChapter 19 Oral Health Promotion in Infants and Preschool Age Children (pages 313-329): Gajanan Vishwanath (Kiran) KulkarniChapter 20 High?Risk Patients: The Frail Older Adult Living in Long?Term Care Homes (pages 330-357): Mary?Lou van der Horst and Donna BowesChapter 21 The Effective Preventive Dental Team (pages 358-376): Ann?Marie C. DePalma and Shirley GutkowskiChapter 22 The Independent Dental Hygienist (pages 377-387): Fran Richardson

Comprehensive Atlas of High Resolution Endoscopy and Narrow Band Imaging By
2007 | 322 Pages | ISBN: 1405158867 | PDF | 25 MB
Won First Prize in the Gastroenterology category of the 2008 BMA Medical Book CompetitionTo help you accelerate your learning curve, Dr. Cohen offers this helpful new atlas with over 900 endoscopic images. Emphasizing conditions for which NBI is particularly useful - such as finding dysplasia in Barrett's mucosa and ulcerative colitis and detecting adenomatous colon polyps - Comprehensive Atlas of High Resolution Endoscopy and Narrowband Imaging gives you an exceptional preview of the future of endoscopy, with a broad new look at normal and abnormal findings throughout the GI tract.The book is divided into three main parts:* The Basics of NBI* Potential Applications of NBI * Atlas of 585 colour images, broken into sections on the pharynx and esophagus, stomach, small intestine, and colon, including correlating histopathology.The accompanying DVD-ROM includes:* 55 video clips containing 2 1/2 hours of annotated video to give you a complete sense of how HRE and NBI work and look in real time, including during therapeutic procedures.* The complete text with a full text and image caption search function* A database of figures from the bookThis spectacular new imaging modality promises to enhance endoscopic decision making in real time, facilitate therapeutic maneuvers, and make tissue sampling more precise. As a tool to guide your mastery of this advance and as a reference for you to use with your patients, colleagues and students, this atlas will find regular use on your desktop and have a noticeable impact on your practice.Content: Chapter 1 Narrowband Imaging: Historical Background and Basis for its Development (pages 1-8): Shigeaki YoshidaChapter 2 An Introduction to Highresolution Endoscopy and Narrowband Imaging (pages 9-22): Kazuhiro GonoChapter 3 Getting Started with Highresolution Endoscopy and Narrowband Imaging (pages 23-30): Ajay Bansal and Prateek SharmaChapter 4 Detection of Superficial Cancer in the Oropharyngeal and Hypopharyngeal Mucosal Sites and the Value of NBI at Qualitative Diagnosis (pages 31-48): Manabu Muto, Atsushi Ochiai and Shigeaki YoshidaChapter 5 Magnifying Endoscopic Diagnosis of Tissue Atypia and Cancer Invasion Depth in the Area of Pharyngo?Esophageal Squamous Epithelium by NBI Enhanced Magnification Image: IPCL Pattern Classification (pages 49-66): Haruhiro Inoue, Makoto Kaga, Yoshitaka Sato, Satoshi Sugaya and Shin?ei KudoChapter 6 Applications of NBI HRE and Preliminary dаta: Barrett's Esophagus and Adenocarcinoma (pages 67-80): Wouter Curvers, Paul Fockens and Jacques BergmanChapter 7 Clinical Application of Magnification Endoscopy with NBI in the Stomach and the Duodenum (pages 81-103): Kenshi Yao, Takashi Nagahama, Fumihito Hirai, Suketo Sou, Toshiyuki Matsui, Hiroshi Tanabe, Akinori Iwashita, Philip Kaye and Krish RagunathChapter 8 Magnifying Endoscopy with NBI in the Diagnosis of Superficial Gastric Neoplasia and its Application for ESD (pages 104-119): Mitsuru Kaise, Takashi Nakayoshi and Hisao TajiriChapter 9 Optical Chromoendoscopy using NBI During Screening Colonoscopy: Its Usefulness and Application (pages 121-148): Yasushi Sano and Shigeaki YoshidaChapter 10 The Significance of NBI Observation for Inflammatory Bowel Diseases (pages 149-160): Takayuki Matsumoto, Tetsuji Kudo and Mitsuo IidaChapter 11 Pharynx and Esophagus Atlas (pages 161-211): Chapter 12 Stomach Atlas (pages 212-244): Chapter 13 Small Intestine Atlas (pages 245-263): Chapter 14 Colon Atlas (pages 264-312):

Compositional Data Analysis: Theory and Applications By
2011 | 390 Pages | ISBN: 0470711353 | PDF | 8 MB
It is difficult to imagine that the statistical analysis of compositional data has been a major issue of concern for more than 100 years. It is even more difficult to realize that so many statisticians and users of statistics are unaware of the particular problems affecting compositional data, as well as their solutions. The issue of ``spurious correlation'', as the situation was phrased by Karl Pearson back in 1897, affects all data that measures parts of some whole, such as percentages, proportions, ppm and ppb. Such measurements are present in all fields of science, ranging from geology, biology, environmental sciences, forensic sciences, medicine and hydrology. This book presents the history and development of compositional data analysis along with Aitchison's log-ratio approach. Compositional Data Analysis describes the state of the art both in theoretical fields as well as applications in the different fields of science. Key Features: Reflects the state-of-the-art in compositional data analysis. Gives an overview of the historical development of compositional data analysis, as well as basic concepts and procedures. Looks at advances in algebra and calculus on the simplex. Presents applications in different fields of science, including, genomics, ecology, biology, geochemistry, planetology, chemistry and economics. Explores connections to correspondence analysis and the Dirichlet distribution. Presents a summary of three available software packages for compositional data analysis. Supported by an accompanying website featuring R code. Applied scientists working on compositional data analysis in any field of science, both in academia and professionals will benefit from this book, along with graduate students in any field of science working with compositional data.Content: Chapter 1 A Short History of Compositional Data Analysis (pages 1-11): John Bacon?ShoneChapter 2 Basic Concepts and Procedures (pages 12-28): Juan Jose Egozcue and Vera Pawlowsky?GlahnChapter 3 The Principle of Working on Coordinates (pages 29-42): Gloria Mateu?Figueras, Vera Pawlowsky?Glahn and Juan Jose EgozcueChapter 4 Dealing with Zeros (pages 43-58): Josep Antoni Martin?Fernandez, Javier Palarea?Albaladejo and Ricardo Antonio OleaChapter 5 Robust Statistical Analysis (pages 59-72): Peter Filzmoser and Karel HronChapter 6 Geostatistics for Compositions (pages 73-86): Raimon Tolosana?Delgado, Karl Gerald van den Boogaart and Vera Pawlowsky?GlahnChapter 7 Compositional VARIMA Time Series (pages 87-103): Carles Barcelo?Vidal, Lucia Aguilar and Josep Antoni Martin?FernandezChapter 8 Compositional Data and Correspondence Analysis (pages 104-113): Michael GreenacreChapter 9 Use of Survey Weights for the Analysis of Compositional Data (pages 114-127): Monique GrafChapter 10 Notes on the Scaled Dirichlet Distribution (pages 128-138): Gianna Serafina Monti, Gloria Mateu?Figueras and Vera Pawlowsky?GlahnChapter 11 Elements of Simplicial Linear Algebra and Geometry (pages 139-157): Juan Jose Egozcue, Carles Barcelo?Vidal, Josep Antoni Martin?Fernandez, Eusebi Jarauta?Bragulat, Jose Luis Diaz?Barrero and Gloria Mateu?FiguerasChapter 12 Calculus of Simplex?Valued Functions (pages 158-175): Juan Jose Egozcue, Eusebi Jarauta?Bragulat and Jose Luis Diaz?BarreroChapter 13 Compositional Differential Calculus on the Simplex (pages 176-190): Carles Barcelo?Vidal, Josep Antoni Martin?Fernandez and Gloria Mateu?FiguerasChapter 14 Proportions, Percentages, PPM: Do the Molecular Biosciences Treat Compositional Data Right? (pages 191-207): David Lovell, Warren Muller, Jen Taylor, Alec Zwart and Chris HelliwellChapter 15 Hardy-Weinberg Equilibrium: A Nonparametric Compositional Approach (pages 208-217): Jan Graffelman and Juan Jose EgozcueChapter 16 Compositional Analysis in Behavioural and Evolutionary Ecology (pages 218-234): Michele Edoardo Raffaele Pierotti and Josep Antoni Martin?FernandezChapter 17 Flying in Compositional Morphospaces: Evolution of Limb Proportions in Flying Vertebrates (pages 235-254): Luis Azevedo Rodrigues, Josep Daunis?i?Estadella, Gloria Mateu?Figueras and Santiago Thio?HenestrosaChapter 18 Natural Laws Governing the Distribution of the Elements in Geochemistry: The Role of the Log?Ratio Approach (pages 255-266): Antonella BucciantiChapter 19 Compositional Data Analysis in Planetology: The Surfaces of Mars and Mercury (pages 267-281): Helmut Lammer, Peter Wurz, Josep Antoni Martin?Fernandez and Herbert Iwo Maria LichteneggerChapter 20 Spectral Analysis of Compositional Data in Cyclostratigraphy (pages 282-289): Eulogio Pardo?Iguzquiza and Javier HerediaChapter 21 Multivariate Geochemical Data Analysis in Physical Geography (pages 290-301): Jennifer McKinley and Christopher David LloydChapter 22 Combining Isotopic and Compositional dаta: A Discrimination of Regions Prone to Nitrate Pollution (pages 302-317): Roger Puig, Raimon Tolosana?Delgado, Neus Otero and Albert FolchChapter 23 Applications in Economics (pages 318-326): Tim FryChapter 24 Exploratory Analysis Using CoDaPack 3D (pages 327-340): Santiago Thio?Henestrosa and Josep Daunis?i?EstadellaChapter 25 robCompositions: An R?package for Robust Statistical Analysis of Compositional Data (pages 341-355): Matthias Templ, Karel Hron and Peter FilzmoserChapter 26 Linear Models with Compositions in R (pages 356-371): Raimon Tolosana?Delgado and Karl Gerald van den Boogaart

Complexity Theory and Project Management By Wanda Curlee, Robert L. Gordon(auth.)
2010 | 399 Pages | ISBN: 0470545968 | PDF | 5 MB
An insightful view on how to use the power of complexity theory to manage projects more successfully Current management practices require adherence to rigid, global responses unsuitable for addressing the changing needs of most projects. Complexity Theory and Project Management shifts this paradigm to create opportunities for expanding the decision-making process in ways that promote flexibility-and increase effectiveness. It informs readers on the managerial challenges of juggling project requirements, and offers them a clear roadmap on how to revise perspectives and reassess priorities to excel despite having an unpredictable workflow. Complexity Theory and Project Management provides remedies through the use of teaching notes, power point slides, a solutions manual, and a toolbox of answers to common project management problems to illustrate how the deployment of complexity theory can make a project more successful. One of the first books covering the subject of complexity theory for project management, this useful guide: Explains the relationship of complexity theory to virtual project management Supplies techniques, tips, and suggestions for building effective and successful teams in the virtual environment Presents current information about best practices and relevant proactive tools Makes a strong case for including complexity theory in PMI's PMBOK Guide Complexity Theory and Project Management gives a firsthand view on the future of complexity theory as a driving force in the management field, and allows project managers to get a head start in applying its principles immediately to produce more favorable outcomes.Content: Chapter 1 Introduction to Complexity Theory (pages 3-13): Chapter 2 Going beyond the Project Management Body of Knowledge (PMBOK®) Guide (pages 15-48): Chapter 3 Virtual Leadership and Complexity (pages 49-67): Chapter 4 Successful Virtual Projects (pages 69-100): Chapter 5 Successful Project Management Strategies of Complexity (pages 103-115): Chapter 6 Virtual Leadership through Complexity (pages 117-134): Chapter 7 How Organizational Culture is the Key to Applying Complexity (pages 135-156): Chapter 8 Cultural Conflict through the Lens of Complexity (pages 157-173): Chapter 9 Cultural Conflict Resolution Strategies (pages 175-190): Chapter 10 Risk Management through the Lens of Complexity (pages 191-196): Chapter 11 SEMCO (Organizational Complexity) (pages 199-206): Chapter 12 Web?based Universities (Multilevel Complexity) (pages 207-215): Chapter 13 Small Team Complexity (pages 217-235): Chapter 14 Leadership of Complexity?Driven Organizations (pages 239-254): Chapter 15 Communities (pages 255-261): Chapter 16 Teams and Complexity (pages 263-286): Chapter 17 Micro?Teams (Tribes) (pages 287-310): Chapter 18 Dealing Appropriately with Change (pages 311-323): Chapter 19 Complexity Tools for Organizations with Virtual Teams (pages 327-356): Chapter 20 Virtual Projects and Complexity Theory (pages 357-366): Chapter 21 Using Complexity to Address a Troubled Project (pages 367-375): Chapter 22 The Future of Complexity (pages 377-387):

Complex Macromolecular Architectures: Synthesis, Characterization, and Self-Assembly By
2011 | 834 Pages | ISBN: 0470825138 | PDF | 110 MB
The field of CMA (complex macromolecular architecture) stands at the cutting edge of materials science, and has been a locus of intense research activity in recent years. This book gives an extensive description of the synthesis, characterization, and self-assembly of recently-developed advanced architectural materials with a number of potential applications. The architectural polymers, including bio-conjugated hybrid polymers with poly(amino acid)s and gluco-polymers, star-branched and dendrimer-like hyperbranched polymers, cyclic polymers, dendrigraft polymers, rod-coil and helix-coil block copolymers, are introduced chapter by chapter in the book. In particular, the book also emphasizes the topic of synthetic breakthroughs by living/controlled polymerization since 2000. Furthermore, renowned authors contribute on special topics such as helical polyisocyanates, metallopolymers, stereospecific polymers, hydrogen-bonded supramolecular polymers, conjugated polymers, and polyrotaxanes, which have attracted considerable interest as novel polymer materials with potential future applications. In addition, recent advances in reactive blending achieved with well-defined end-functionalized polymers are discussed from an industrial point of view. Topics on polymer-based nanotechnologies, including self-assembled architectures and suprastructures, nano-structured materials and devices, nanofabrication, surface nanostructures, and their AFM imaging analysis of hetero-phased polymers are also included. Provides comprehensive coverage of recently developed advanced architectural materialsContent: Chapter 1 Cyclic and Multicyclic Topological Polymers (pages 1-19): Takuya Yamamoto and Yasuyuki TezukaChapter 2 Ultrarapid Approaches to Mild Macromolecular Conjugation (pages 21-52): Andrew J. Inglis and Christopher Barner?KowollikChapter 3 Synthesis and Self?Assembly of Hydrogen?Bonded Supramolecular Polymers (pages 53-95): Wolfgang H. Binder, Claudia Enders, Florian Herbst and Katharina HackethalChapter 4 Recent Synthetic Developments in Miktoarm Star Polymers with More than Three Different Arms (pages 97-132): Akira Hirao, Mayumi Hayashi, Tomoya Higashihara and Nikos HadjichristidisChapter 5 Precise Synthesis of Dendrimer?Like Star?Branched Polymers, a New Class of Well?Defined Hyperbranched Polymers (pages 133-167): Hee?Soo Yoo and Akira HiraoChapter 6 Arborescent Polymers with a Mesoscopic Scale (pages 169-194): Toufic Nabil Aridi and Mario GauthierChapter 7 Hyperbranched Glyco?Conjugated Polymers (pages 195-227): Toshifumi Satoh and Toyoji KakuchiChapter 8 Highly Branched Functional Polymer Architectures by Click?Chemistry Strategies (pages 229-265): Mieke Lammens and Filip Du PrezChapter 9 Living Alkene Polymerization for Polyolefin Architectures (pages 267-316): Amelia M. Anderson?Wile, Joseph B. Edson and Geoffrey W. CoatesChapter 10 Precision Polyolefins (pages 317-347): Erik B. Berda and Kenneth B. WagenerChapter 11 Polyhomologation: The Living Polymerization of Ylides (pages 349-376): Jun Luo and Kenneth J. SheaChapter 12 Phenylenevinylene Homopolymers and Block Copolymers via Ring?Opening Metathesis Polymerization (pages 377-393): Chin?Yang Yu and Michael L. TurnerChapter 13 Block Copolymers Containing Rod Segments (pages 395-429): Tomoya Higashihara and Mitsuru UedaChapter 14 Synthesis of Well?Defined Poly(meth)acrylamides with Varied Stereoregularity by Living Anionic Polymerization (pages 431-460): Takashi IshizoneChapter 15 Complex Macromolecular Chimeras (pages 461-489): Hermis Iatrou, Marinos Pitsikalis, Georgios Sakellariou and Nikos HadjichristidisChapter 16 Self?Assembly and Applications of Polyferrocenylsilane Block Copolymers (pages 491-526): George R. Whittell, Jessica Gwyther, David A. Rider and Ian MannersChapter 17 Functional Polymeric Nanostructures Prepared by Self?Assembly and Beyond (pages 527-567): Rachel K. O'ReillyChapter 18 Morphologies of Block and Star?Branched Polymers with Three Components (pages 569-591): Hirokazu HasegawaChapter 19 Morphologies and Photophysical Properties of Conjugated Rod-Coil Block Copolymers (pages 593-622): Chi?Ching Kuo, Cheng?Liang Liu and Wen?Chang ChenChapter 20 Bulk Self?Assembly of Linear Hybrid Polypeptide?Based Diblock and Triblock Copolymers (pages 623-645): Sebastien LecommandouxChapter 21 AFM Study of Comb (Co)Polymers with Complex Chain Architecture (pages 647-683): Michel Schappacher and Alain DeffieuxChapter 22 Tunable Thermoresponsive Polymers by Molecular Design (pages 685-715): Richard HoogenboomChapter 23 Fluorine?Containing Block Copolymers: Synthesis and Application as a Template for Nanocellular and Porous Structures Using Supercritical Carbon Dioxide (pages 717-737): Hideaki Yokoyama and Kenji SugiyamaChapter 24 Architectural Polymers, Nanostructures, and Hierarchical Structures from Block Copolymers (pages 739-761): Ian Wyman and Guojun LiuChapter 25 Block Copolymer Nanostructured Thin Films for Advanced Patterning (pages 763-790): Michelle A. Chavis, Evan L. Schwartz and Christopher K. OberChapter 26 Ring Polymers: Effective Isolation and Unique Properties (pages 791-821): Haskell W. Beckham

Compendium of Organic Synthetic Methods, Volume 8 By
1995 | 648 Pages | ISBN: 0471573191 | PDF | 25 MB
More than a one-volume listing of synthetic methods, Compendium of Organic Synthetic Methods offers chemists a highly focused and selective look at several thousand functional group transformations. Used by more professionals than any comparable reference on the market, this valuable desktop resource provides quick access to the recipes of the newest, most useful reactions and transformations. It also affords professionals an unparalleled opportunity to browse the vast body of recent literature for new reactions and transformations that may be of interest. Featuring 1,200 more entries than its predecessor, Volume 8 covers functional group transformations and carbon-carbon bond forming reactions appearing in the literature from 1990 through 1992. It presents approximately 1,400 examples of published reactions for the preparation of monofunctional compounds and approximately 1,640 examples of reactions that prepare difunctional compounds with various functional groups. It also features 60 more reviews than Volume 7. As in all the previous Compendium volumes, the classification schemes used allow for quick and easy reference and information retrieval. Chemical transformations are classified first by the reacting functional group of the starting material and then by the functional group formed. The transformation, major reagents that effect the transformation, yield percentage, and stereochemistry are all clearly shown. The Compendium also includes indices for both monofunctional and difunctional compounds as an efficient means of guiding you to specific classes of transformations. Compendium of Organic Synthetic Methods, Volume 8 provides professional chemists and students unparalleled access to the wealth of methods, reactions, and transformations in contemporary organic chemistry.Content:

Comparing Clinical Measurement Methods: A Practical Guide By Bendix Carstensen(auth.)
2010 | 166 Pages | ISBN: 0470694238 | PDF | 3 MB
This book provides a practical guide to analysis of simple and complex method comparison data, using Stata, SAS and R. It takes the classical Limits of Agreement as a starting point, and presents it in a proper statistical framework. The model serves as a reference for reporting sources of variation and for providing conversion equations and Descriptions between methods for practical use, including prediction uncertainty. Presents a modeling framework for analysis of data and reporting of results from comparing measurements from different clinical centers and/or different methods. Provides the practical tools for analyzing method comparison studies along with guidance on what to report and how to plan comparison studies and advice on appropriate software. Illustrated throughout with computer examples in R. Supported by a supplementary website hosting an R-package that performs the major part of the analyses needed in the area. Examples in SAS and Stata for the most common situations are also provided. Written by an acknowledged expert on the subject, with a long standing experience as a biostatistician in a clinical environment and a track record of delivering training on the subject. Biostatisticians, clinicians, medical researchers and practitioners involved in research and analysis of measurement methods and laboratory investigations will benefit from this book. Students of statistics, biostatistics, and the chemical sciences will also find this book useful.Content: Chapter 1 Introduction (pages 1-3): Chapter 2 Method Comparisons (pages 5-15): Chapter 3 Howto... (pages 17-20): Chapter 4 Two Methods with a Single Measurement on Each (pages 21-47): Chapter 5 Replicate Measurements (pages 49-65): Chapter 6 Several Methods of Measurement (pages 67-69): Chapter 7 A General Model for Method Comparisons (pages 71-97): Chapter 8 Transformation of Measurements (pages 99-106): Chapter 9 Repeatability, Reproducibility and Coefficient of Variation (pages 107-114): Chapter 10 Measures of Association and Agreement (pages 115-126): Chapter 11 Design of Method Comparison Studies (pages 127-131): Chapter 12 Examples Using Standard Software (pages 133-147): Chapter 13 The MethComp Package for R (pages 149-152):

Comparative Pharmacokinetics: Principles, Techniques, and Applications, Second Edition By Jim E. Riviere(auth.)
2011 | 442 Pages | ISBN: 0813829933 | PDF | 7 MB
Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner. Developed as a tool for ensuring that pharmacokinetics studies are properly designed and correctly interpreted, the book provides complete coverage of the conceptual basis of pharmacokinetics as used for quantifying biological processes from the perspectives of physiology and medicine. New chapters have been added on quantitative structure permeability relationships and bioequivalence, and a number of existing chapters have been significantly revised and expanded to provide a current resource for veterinary and comparative pharmacokinetics.Content: Chapter 1 Introduction (pages 3-11): Chapter 2 Principles of Drug Movement in the Body (pages 13-25): Chapter 3 Quantitative Structure-Permeability Relationships (pages 27-38): Xin?Rui XiaChapter 4 Absorption (pages 39-71): Chapter 5 Distribution (pages 73-90): Jennifer BuurChapter 6 Renal Elimination (pages 91-111): Chapter 7 Hepatic Biotransformation and Biliary Excretion (pages 113-141): Ronald BaynesChapter 8 Compartmental Models (pages 143-186): Chapter 9 Noncompartmental Models (pages 187-206): Chapter 10 Nonlinear Models (pages 207-223): Chapter 11 Physiological Models (pages 225-240): Teresa LeavensChapter 12 Dosage Regimens (pages 241-254): Chapter 13 Simultaneous Pharmacokinetic-Pharmacodynamic Modeling (pages 255-294): Pierre?Louis ToutainChapter 14 Study Design and Data Analysis (pages 295-313): Jason ChittendenChapter 15 Bioequivalence Studies (pages 315-346): Marilyn MartinezChapter 16 Population Pharmacokinetic Models (pages 347-378): Jason ChittendenChapter 17 Dosage Adjustments in Disease States (pages 379-397): Jennifer DavisChapter 18 Interspecies Extrapolations (pages 399-412): Chapter 19 Tissue Residues and Withdrawal Times (pages 413-424):

Comparative Diagnostic Pharmacology: Clinical and Research Applications in Living-System Models By C.P. Coyne(auth.)
2006 | 933 Pages | ISBN: 0813817536 | PDF | 8 MB
Comparative Diagnostic Pharmacology: Clinical and Research Applications in Living-System Models is the first evidence-based reference text devoted exclusively to the subject of applying pharmaceutical and biopharmaceutical agents as diagnostic probes in clinical medicine and investigative research.This unique and groundbreaking book is a versatile guide for clinicians and researchers interested in using pharmacologic agents to: Diagnose disease Assess physiological processes Identify the appropriateness of a therapeutic agent Determine appropriate dosing for therapeutic use.Extensively referenced and organized by major body systems, individual topics are listed in an evidence-based format according to specific disease processes or physiological processes of interest. Each entry also includes information on the mechanism of action, administration, and diagnostic interpretation.Descriptions have been provided for the application of diagnostic pharmaceuticals to assess a wide spectrum of diseases and physiological processes relevant to the fields of veterinary and human medicine. Comparative Diagnostic Pharmacology is useful not merely for pharmaceutical-oriented research investigations, but it will also prove invaluable for the monitoring and evaluation of physiological responses and disease processes in animal models.Content: Chapter 1 Cardiovascular System (pages 5-60): Chapter 2 Central Nervous System (pages 61-127): Chapter 3 Endocrine System (pages 129-177): Chapter 4 Gastrointestinal System (pages 179-220): Chapter 5 Hematopoietic System (pages 221-266): Chapter 6 Hepatic System (pages 267-335): Chapter 7 Integumentary System (pages 337-339): Chapter 8 Musculoskeletal System (pages 341-349): Chapter 9 Reproductive System (pages 351-354): Chapter 10 Renal and Urinary Systems (pages 355-373): Chapter 11 Respiratory System (pages 375-403): Chapter 12 Cancer/Neoplastic Disease (pages 407-424): Chapter 13 Genetics and Nucleic Acids (pages 425-438): Chapter 14 Inflammation, Infection, and Sepsis (pages 439-453): Chapter 15 Metabolism, Electrolytes, and Hypoxia (pages 455-470): Chapter 16 Fluorescent and Pigment Dye Reagents (pages 473-516): Chapter 17 Magnetic Resonance Imaging (MRI) (pages 517-567): Chapter 18 Nuclear Planar Scintigraphy (pages 569-675): Chapter 19 Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) (pages 677-729): Chapter 20 Radiographic Image?Enhancing Agents (pages 731-764): Chapter 21 Ultrasonography (pages 765-808): Chapter 22 Biological and Synthetic Delivery Modalities (pages 811-905):