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Autoimmunity Methods and Protocols

Autoimmunity Methods and Protocols
Autoimmunity: Methods and Protocols By Andras Perl (auth.), Andras Perl MD, PhD (eds.)
2004 | 432 Pages | ISBN: 1588292312 | PDF | 4 MB
Autoimmunity-which affects up to 10% of the world's population-can damage nearly every tissue or cell type of the human body with greatly debilitating or fatal results. In Autoimmunity: Methods and Protocols, expert medical researchers describe in step-by-step detail molecular techniques and in vitro/in vivo model systems for discovering the causes of autoimmunity, as well as how best it may be regulated. The methods to assess the immunological and biochemical pathways relevant for pathogenesis include identifying susceptibility genes, intercellular signaling via cytokines, intracellular signaling through the T-cell receptor, signal processing via protein kinases, identification and enumeration of antigen-specific T cells and autoantibodies, and the dysregulation of apoptosis and its role in modification of self-antigens. Additional protocols serve to establish the presence of and assess inflammatory arthritis, systemic lupus erythematosus, insulin-dependent diabetes mellitus, multiple sclerosis, myocarditis, thyroiditis, scleroderma, uveitis, and vitiligo. These methods can be used to assess the genetic, immunological, and biochemical parameters underlying spontaneous or exogenous antigen-induced diseases. The protocols follow the successful Methods in Molecular Medicine™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Innovative and easy to follow, Autoimmunity: Methods and Protocols offers today's investigators a cutting-edge collection of readily reproducible methods for establishing and interrogating human and animal models of autoimmune diseases.

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Art History Vol 1, 6th Edition

Art History Vol 1, 6th Edition
Art History Vol 1
English | 2018 | ISBN: 0134479270 | 641 Pages | PDF | 265 MB
Art History brings the history of art to life for a new generation of students. It is global in scope, inclusive in its coverage, and warm and welcoming in tone. The guiding vision of Art History is that the teaching of art history survey courses should be filled with equal delight, enjoyment, and serious learning, while fostering an enthusiastic and educated public for the visual arts. The Sixth Edition has been revised to reflect new discoveries, recent research, and fresh interpretive perspectives, as well as to address the changing needs of both students and educators.

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Arduino Projects with Tinkercad

Arduino Projects with Tinkercad
Arduino Projects with Tinkercad: Designing and programming Arduino-based electronics projects using Tinkercad (Arduino | Introduction and Projects) by M.Eng. Johannes Wild
English | May 18, 2022 | ISBN: 3987420375 | 77 pages | PDF | 2.93 Mb
In this book we will create together and step by step five exciting and great projects using the microcontroller Arduino Uno. We will use Autodesk's free Tinkercad software and its block-based programming approach. Also, in each of the projects we will use sensors, such as a temperature sensor, or even an ultrasonic sensor and other components.

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Arduino Projects with Tinkercad Part 2 Design & program advanced Arduino-based electronics projects with Tinkercad

Arduino Projects with Tinkercad  Part 2 Design & program advanced Arduino-based electronics projects with Tinkercad
Arduino Projects with Tinkercad | Part 2: Design & program advanced Arduino-based electronics projects with Tinkercad by M.Eng. Johannes Wild
English | July 8, 2022 | ISBN: 3987420472 | 121 pages | PDF | 6.27 Mb
Attention:This book is the sequel to the book "Arduino Projects with Tinkercad" as well as to the beginner book "Arduino Step by Step". This book is aimed at advanced Arduino users and therefore requires some basic knowledge. It is best to work through the two books mentioned above first before starting with this book.

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Architectural Factors for Infection and Disease Control

Architectural Factors for Infection and Disease Control
Architectural Factors for Infection and Disease Control
English | 2023 | ISBN: 1032102667 | 313 Pages | PDF (True) | 27 MB
This edited collection explores disease transmission and the ways that the designed environment has promoted or limited its spread. It discusses the many design factors that can be used for infection and disease control through lenses of history, public health, building technology, design, and education.

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Applied Demography and Public Health

Applied Demography and Public Health
Applied Demography and Public Health By Nazrul Hoque, Mary A. McGehee, Benjamin S. Bradshaw (auth.), Nazrul Hoque, Mary A. McGehee, Benjamin S. Bradshaw (eds.)
2013 | 391 Pages | ISBN: 9400761392 | PDF | 5 MB
This book combines the disciplines of applied demography and public health by describing how applied demographic techniques can be used to help address public health issues. Besides addressing the impact of aging on health and health-related expenditure, cause-specific mortality, and maternal health and morbidity, the book provides several chapters on special analysis and methodological issues.The chapters provide a number of resources and tools that can be used in conducting research aimed at promoting public health. These resources include information on a variety of health research datasets, different statistical methodologies for analyzing health-related data and developing concepts related to health status, methodologies for forecasting or projecting disease incidences and associated costs, and discussions of demographic concepts used to measure population health status.

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Antibody Engineering Protocols

Antibody Engineering Protocols
Antibody Engineering Protocols By George Johnson, Tai Te Wu, Elvin A. Kabat (auth.), Sudhir Paul (eds.)
1995 | 450 Pages | ISBN: 0896032752 | PDF | 9 MB
This comprehensive collection of recently developed methods for producing new antibody reagents by immunization and recombinant DNA techniques contains ready-to-use protocols that illuminate current areas of research on antibody structure, functions, and applications. The methods can be applied in basic immunological studies involving antibody specificity, catalysis, and evolution, and in the isolation of rare antibodies by phage display technology and the engineering of new antibodies by mutagenesis. They offer insight into new ways of developing clinically useful antibody reagents. Antibody Engineering Protocols constitutes a single-source volume for laboratory investigators who want to minimize extensive literature and methodology searches and to work productively in their fields with reproducible step-by-step protocols.

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An Extraordinary Scandal The Westminster Expenses Crisis and Why It Still Matters

An Extraordinary Scandal The Westminster Expenses Crisis and Why It Still Matters
Emma Crewe, "An Extraordinary Scandal: The Westminster Expenses Crisis and Why It Still Matters"
English | ISBN: 191220875X | 2020 | 320 pages | EPUB | 2 MB
A parliamentary scandal that dominates the headlines. The resignation of major party figures. Commentators and citizens wondering if the British government-and the people's faith in it-will survive. Before Brexit, another major crisis rocked the foundation of government in the country: the expenses scandal of 2009.

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Alvar Aalto and the Future of Architecture

Alvar Aalto and the Future of Architecture
Alvar Aalto and the Future of Architecture
English | 2023 | ISBN: 0367749726 | 251 Pages | PDF (True) | 30 MB
In the contemporary practice of architecture, digital design and fabrication are emergent technologies in transforming how architects present a design and form a material strategy that is responsible, equitable, sustainable, resilient, and forward-looking. This book exposes dialogue between history, theory, design, construction, technology, and sensory experience by means of digital simulations that enhance the assessment and values of our material choices. It offers a critical look to the past to inspire the future.

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